This week Oregon made history, becoming the first state in the country to legalize psilocybin mushrooms for therapeutic use. The state now has to create a new program from scratch. The Oregon Health Authority will run it, and with the passage of Measure 109, it has two years to develop a program that would allow for use of the drug in licensed centers. Psilocybin is the hallucinogenic compound in magic mushrooms. Fifty-six percent of Oregon voters approved its use.